23 Jul Prevalence of Pre-Pregnancy Diabetes, Obesity and Hypertension in Canada
Objective: Pre-existing diabetes mellitus (D), obesity (O) and chronic hypertension (H) can each alter the natural course of a pregnancy for mother and child, especially when they cluster together. As the prevalence of various combinations of D, O and H is unknown, the current study was undertaken. Methods: This population-based cross-sectional study included 506,483 singleton and twin livebirth and stillbirth deliveries in Ontario, Canada, occurring at ≥ 20 weeks gestation. All hospital births from 2012-2016 were identified in the Better Outcomes Registry & Network Information System. The prevalence per 1000 births (95% confidence interval [CI]) of D, O and H were calculated, and their varying combinations. Prevalence estimates were also stratified by singleton and twin gestations, maternal age and parity categories, and maternal ethnicity. O was defined as a pre-pregnancy body mass index ≥ 30 kg/m2. Results: During the study period, 5493 women (10.8 per 1000 births, 95% CI 10.6 to 11.1) had D, 90,177 (178.2 per 1000, 95% CI 177.0 to 179.3) had O and 5667 (11.2 per 1000, 95% CI 10.9 to 11.5) had H. The prevalence of DO was 4.8 per 1000, DH 1.0 per 1000 and OH 5.5 per 1000, while 359 women (0.71 per 1000) had all three combined. D and H each linearly increased with rising maternal age, along with their combinations, and to some degree with higher parity. The combination of O and H was highest among women of black ancestry (14.5 per 1000), and lowest among those of Asian ancestry (3.0 per 1000). Conclusion: D, O and H are common conditions in pregnancy, both alone and in various combinations. These data can be used to assess the impact of each state on current and future maternal and perinatal health.
Contact for this study:
Karizma Mawjee, firstname.lastname@example.org