Prevalence and Risk Factors of Preeclampsia in Twin Pregnancies - DOH-Net
The Diabetes, Obesity and Hypertension in Pregnancy Research Network (DOH-Net) is a multi-disciplinary research team of obstetrical, midwifery and maternal-fetal medicine specialists.
DOH-Net, research, diabetes, hypertension, obesity, pregnancy, gestational diabetes, diabetes, obesity and hypertension in pregnancy research network, Sunnybrook Health Sciences Centre, St. Michael's Hospital, McMaster University, obstetrics, midwife, maternal-fetal medicine, specialists, researchers, Toronto, Ontario, Canada, Hamilton, Greater Toronto Area, GTA
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Prevalence and Risk Factors of Preeclampsia in Twin Pregnancies

Although  the  development  of  preeclampsia  (PE) is  thought  to  be  the  result  of  placental  dysfunction, it  is  still  unclear  if  the  development  of  preeclampsia  is  the  same  in  both  single  and  twin  pregnancies.  Previous  studies  reported  conflicting  results  regarding  the  incidence,  characteristics  and  risk  factors  for  PE  in  twins  compared  with  singleton  pregnancies.  Different  results  were  also  reported  regarding  twins  and  hypertensive  disorders  in  pregnancy.  These  studies  are  limited  by  lack  of  adjustments  for  confounders  and  small  sample  sizes. This retrospective study compares the rate and risk factors for gestational hypertension (GHTN) and PE between twins and singleton pregnancies using  a  large  provincial  population-based  cohort  from the Better Outcomes Registry and Network (BORN) database while  controlling  for  potential  confounding  variables. This study includes all women who gave birth in Ontario, Canada between April 2012 and March 2016.

Contact for this study:
Isabel Arruda, isabel.arruda@sunnybrook.ca